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29 января 2021
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№204, январь 2021
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Минздрав описал различия «Спутника V» и вакцины от «Вектора»
Министерство здравоохранения рассказало о различиях в действии вакцин «Спутник V» и «ЭпиВакКорона», разработанных разными российскими научными центрами. Сообщение пресс-службы ведомства опубликовано 28 января.
Препарат «Спутник V» (Гам-Ковид-Вак), созданный Центром имени Н. Ф. Гамалеи Минздрава России, состоит из обезвреженных частиц аденовируса, не размножающихся в организме человека. Генетическая основа такого аденовируса была удалена, а вместо неё введен ген с кодом генетической информации коронавируса, содержащегося в особом белке. Такой белок помогает организму вызвать иммунную реакцию на вирус и выработать антитела, которые в дальнейшем будут защищать его от инфекции. Процесс вакцинации состоит из двух этапов: первый запускает иммунный ответ, а второй «разгоняет» и усиливает его. Каждый этап подразумевает укол с аденовирусами разных типов с интервалом 21 день.
Вакцина «ЭпиВакКорона», разработанная в новосибирском центре «Вектор», содержит искусственно синтезированные пептиды (небольшие белки) COVID-19. Такие небольшие фрагменты вирусных белков распознаются иммунными клетками привитого человека, и к ним вырабатываются антитела. Таким образом, в будущем, при контакте с вирусом, иммунная система сможет распознать его по таким же пептидам и предотвратить заболевание. Вакцинация препаратом также проводится в два этапа с интервалом 14–21 день.
Напомним, что сейчас к регистрации готовится третья вакцина для профилактики коронавируса, разработанная Центром исследований и разработки иммунобиологических препаратов имени М. П. Чумакова. В отличие от других препаратов, она создана на основе инактивированного вируса. Подобным образом, например, изготавливают вакцины для борьбы с полиомиелитом или энцефалитом.
Катрен Стиль
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