Аспирин способен восстанавливать зубы
21 сентября 2017
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№164, сентябрь 2017
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Аспирин способен восстанавливать зубы
Ирландские ученые из Университета Квинс в Белфасте (Queen»s University Belfast) обнаружили, что аспирин может быть альтернативой пломбировке зубов. Результаты такого исследования были представлены 7 сентября 2017 года на Ежегодной конференции Британского общества по исследованиям ротовой полости и зубов (British Society for Oral and Dental Research Annual Conference).
Исследователи, объединив методы геномики и биоинформатики, показали, что аспирин способен стимулировать работу стволовых клеток в зубах, таким образом способствуя самовосстановлению путем регенерации разрушенных структур.
Терапия стволовыми клетками зуба вместе с небольшими дозами аспирина значительно увеличивала минерализацию и экспрессию генов, отвечающих за формирование дентина, — части зуба, которая обычно повреждается при разрушении.
В сочетании с известными противовоспалительным и обезболивающим эффектами аспирина такое открытие может предоставить возможность контроля над воспалительными процессами в нервных окончаниях зуба, в то время как происходит его естественное восстановление.
Поскольку аспирин является лицензированным для лечения людей препаратом, такой подход может быть доступным инновационным решением, дающим возможность самовосстановления зубов.
Следующим шагом команда планирует разработать подходящую систему доставки для проверки эффективности препарата в клинических испытаниях. Новый метод не только поможет увеличить срок службы зубов человека, но и сможет значительно сэкономить средства системами здравоохранения во всем мире.
Источник:
Medicalxpress
Катрен Стиль
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