Катрен Стиль
Изменилась инструкция по применению «АЦЦ Лонг»
Владелец регистрационного удостоверения на препарат «АЦЦ Лонг», компания АО «Сандоз» сообщает об изменении инструкции по применению этого ЛС согласно последним данным по безопасности его применения. Соответствующее информационное письмо имеется в распоряжении редакции «Катрен-Стиль».
В раздел «Побочное действие» инструкции теперь добавлена новая нежелательная реакция — «стоматит» с частотой «нечасто». Также в разделе указана информация о случаях развития коллапса (частота неизвестна) и единичных случаях развития кровотечений на фоне применения препарата.
Кроме этого, изменён раздел «Взаимодействие с другими лекарственными препаратами» в части применения ЛС совместно с нитроглицерином:
«Одновременное применение с ацетилцистеином может привести к усилению сосудорасширяющего и антитромбоцитарного эффектов нитроглицерина. Если требуется совместное применение нитроглицерина и ацетилцистеина, то следует контролировать состояние пациента на предмет потенциального развития артериальной гипотензии (иногда тяжёлой, может проявляться головной болью)».
Ранее в отношении взаимодействия ацетилцистеина с нитроглицерином было указано только то, что это может вызвать снижение артериального давления и головную боль.
В раздел «Особые указания» добавлена информация о необходимости соблюдения осторожности при применении ацетилцистеина у пациентов с непереносимостью гистамина, а также о том, что следует избегать применения препарата у пациентов с почечной или печёночной недостаточностью во избежание дополнительного образования азотистых соединений.
Ранее Минздрав распорядился внести новое противопоказание в инструкции по применению 12 нестероидных противовоспалительных препаратов.
23 апреля 2021
Фото: depositphotos.com
Выпуск: №207, апрель 20214141 просмотров
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4141 просмотров
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