Катрен СтильПрепараты от остеопороза способны снизить риск инфаркта и инсульта
Группа ученых из Университета Гонконга (University of Hong Kong) установила, что применение алендроновой кислоты при остеопорозе или переломе бедра значительно снижает риск смерти от сердечно-сосудистых заболеваний, таких как инфаркт или инсульт. Статья об этом опубликована 9 мая в научном журнале Journal of Bone and Mineral Research.
Ученые проанализировали записи 18 170 пациентов, получивших перелом бедра в период с 2005 по 2013 год. В 4 602 случаях больные принимали препараты от остеопороза (алендроновую кислоту и другие азотсодержащие бисфосфонаты). Данные были взяты из реестра управления по делам государственных больниц и клиник (Hong Kong Hospital Authority). Наблюдения учитывали историю пациентов до ноября 2016 года.
Исследование показало, что применение алендроновой кислоты на 67 % снижало риск смерти от сердечно-сосудистых заболеваний, и в частности на 45 % — от инфаркта, в течение года после лечения. Кроме этого, применение алендроновой кислоты снижало вероятность инсульта на 18 % в течение 5 лет после приема препарата. Применение других бисфосфонатов показало схожие результаты, но наибольшие показатели снижения риска были именно у алендроновой кислоты.
Ученые отмечают, что их работа может повлиять на терапию остеопороза, поскольку теперь пациенты будут знать, что применение бисфосфонатов (в частности алендроновой кислоты), несмотря на побочные эффекты, может также иметь и положительное влияние на сердечно-сосудистую систему.
14 мая 2018
Выпуск: №172, май 20181985 просмотров
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