Катрен СтильУченые открыли возможность диагностировать болезнь Альцгеймера по анализу крови
Японские ученые из Национального центра гериатрии и геронтологии (National Center for Geriatrics and Gerontology) разработали новую методику анализа крови, которая может диагностировать у пациента болезнь Альцгеймера. Об этом 1 февраля пишет онлайн-издание Japan Today.
В основе метода, разработанного японскими медиками, лежит использование специальных биомаркеров, которые выделяют из крови человека вещества, связанные с бета-амилоидами (пептидами, скопление которых в мозге человека считается одной из причин развития болезни Альцгеймера). Из выделенных веществ методом масс-спектрометрии определяется количество содержащихся в организме бета-амилоидов.
В настоящий момент для определения амилоидных бляшек (излишнего накопления пептидов) используются ПЭТ (позитронно-эмиссионная томография) и люмбальная пункция. Однако эти способы диагностики либо болезненны, либо высокозатратны. Для анализа крови по методу японских ученых требуется только 0,5 мл крови пациента.
Ученые протестировали новый способ анализа на 232 пожилых людях из Японии и Австралии в возрасте от 60 до 90 лет. Среди них были как пациенты, страдающие болезнью Альцгеймера, так и не страдающие ей. Анализ крови сравнивался с результатами позитронно-эмиссионной томографии. В 90 % случаев диагноз пациентов совпадал.
Японские ученые рассчитывают, что при поддержке производителей лабораторного оборудования новая методика выявления болезни Альцгеймера получит распространение уже в ближайшем будущем.
2 февраля 2018
Выпуск: №169, февраль 20181657 просмотров
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