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Ученые создали гибрид человека и свиньи: cоздание такого рода химер поможет в проверке лекарств до перехода к испытаниям на людях
Ученые создали гибрид человека и свиньи: cоздание такого рода химер поможет в проверке лекарств до перехода к испытаниям на людях
Американским ученым из Института биологических исследований Солка (Salk Institute for Biological Studies) удалось вырастить первый в мире эмбрион, состоящий из клеток свиньи и человека. Результаты эксперимента были опубликованы 26 января в научном журнале Cell.
Исследователи вводили в эмбрион свиньи стволовые клетки человека, после чего имплантировали его в свиную матку. Затем эмбрионам давали развиваться в течение 28 дней. По истечении этого времени стволовые клетки развились в предшественников различных видов тканей, таких как сердце и печень. Во время развития эмбрион свиньи состоял в том числе и из человеческих клеток.
Хотя из 2075 подсаженных эмбрионов за 28 дней развились лишь 186 штук, ученые считают эксперимент удачным.«Впервые человеческие клетки росли внутри крупного животного», — заявил один из авторов исследования профессор Хуан Карлос Исписуа Бельмонте в интервью BBC.
Создание такого рода гибридов поможет в проверке лекарств до перехода к испытаниям на людях и при изучении начала развития человеческих заболеваний. В будущем на основе таких экспериментов можно будет создать технологию по выращиванию человеческих органов внутри животных.
Согласно постановлению Национальных институтов здравоохранения США (National Institutes of Health), государственное финансирование подобных исследований запрещено, поэтому эксперимент проводился на частные средства.
Источники:
BBC RussiaCell
30 января 2017
Фото: www.istockphoto.com/shironosov
Выпуск: №156, январь 20171966 просмотров
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