Катрен Стиль
Ученые обнаружили кровеносные сосуды в костях человека
Исследователи из немецкого Университета Дуйсбург-Эссена установили, что в костях человека содержатся каналы, позволяющие клеткам крови проникать к костному мозгу и обратно. Ранее о существовании подобной анатомической структуры было неизвестно. Подробное исследование опубликовано в журнале Nature.
Открытие произошло случайно в ходе изучения флуоресцентно окрашенных клеток крови мышей. Ученые отметили, что такие клетки способны проходить через твердые кости животного. Затем они начали целенаправленно изучать берцовые кости мышей с применением вещества этилциннамат, которое делает костную ткань более прозрачной.
С помощью флуоресцентной и рентгеновской микроскопии исследовательской группе удалось определить наличие мельчайших сосудов, проходящих через кортикальный слой. В кости голени содержалось около тысячи таких транскортикальных сосудов. По оценкам ученых, через такие сосуды проходит 80 % артериальной и 60 % венозной крови.
Следующим шагом стало исследование человеческих костей. При помощи магнитно-резонансной томографии авторы эксперимента провели сканирование ноги добровольца из числа ученых. Сканирование показало наличие в кости крошечных отверстий, схожим с мышиными. Таким образом ученые сделали вывод, что подобные транскортикальные сосуды существуют и в организме человека.
Это может объяснить, например, быструю реакцию организма на метод внутрикостной инфузии ряда лекарственных препаратов. По словам ученых, для более подробного изучения этого открытия понадобятся дополнительные исследования.
23 января 2019
Фото: depositphotos.com
Выпуск: №180, январь 20191842 просмотров
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